Hao Y. Kueh, Ph.D.

Affiliations: 
2008 Harvard University, Cambridge, MA, United States 
Area:
Microtubules, Actin, Mitosis, Cell cycle
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"Hao Kueh"

Parents

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Timothy J. Mitchison grad student 2008 Harvard
 (Actin turnover dynamics in cells.)
Ellen V. Rothenberg post-doc 2008-2016 Caltech
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Publications

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Ng KK, Yui MA, Mehta A, et al. (2018) A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment. Elife. 7
Ng KK, Yui MA, Mehta A, et al. (2018) Author response: A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment Elife
Longabaugh WJR, Zeng W, Zhang JA, et al. (2017) Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network. Proceedings of the National Academy of Sciences of the United States of America. 114: 5800-5807
Manesso E, Kueh HY, Freedman G, et al. (2016) Irreversibility of T-Cell Specification: Insights from Computational Modelling of a Minimal Network Architecture. Plos One. 11: e0161260
Kueh HY, Yui MA, Ng KK, et al. (2016) Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment. Nature Immunology. 17: 956-65
Rothenberg EV, Kueh HY, Yui MA, et al. (2016) Hematopoiesis and T-cell specification as a model developmental system. Immunological Reviews. 271: 72-97
Rothenberg EV, Champhekar A, Damle S, et al. (2013) Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment. Cold Spring Harbor Symposia On Quantitative Biology. 78: 31-41
Kueh HY, Champhekar A, Champhekhar A, et al. (2013) Positive feedback between PU.1 and the cell cycle controls myeloid differentiation. Science (New York, N.Y.). 341: 670-3
Li L, Zhang JA, Dose M, et al. (2013) A far downstream enhancer for murine Bcl11b controls its T-cell specific expression. Blood. 122: 902-11
Manesso E, Chickarmane V, Kueh HY, et al. (2013) Computational modelling of T-cell formation kinetics: output regulated by initial proliferation-linked deferral of developmental competence. Journal of the Royal Society, Interface. 10: 20120774
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