Matthew B. Denholtz, Ph.D.

Affiliations: 
2013 Molecular Biology University of California, Los Angeles, Los Angeles, CA 
Area:
X Chromosome inactivation
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"Matthew Denholtz"

Parents

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Kathrin Plath grad student 2013 UCLA
 (Long-range chromatin contacts reveal a role for the pluripotency and Polycomb networks in genome organization.)
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Publications

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Zhu Y, Denholtz M, Lu H, et al. (2020) Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization. Genes & Development
Bortnick A, He Z, Aubrey M, et al. (2020) Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs. Cell Reports. 31: 107876
Bortnick A, He Z, Aubrey M, et al. (2020) Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs. Cell Reports. 31: 107470
Denholtz M, Zhu Y, He Z, et al. (2020) Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program. Genes & Development
Isoda T, Moore AJ, He Z, et al. (2017) Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 171: 103-119.e18
Zhu Y, Gong K, Denholtz M, et al. (2017) Comprehensive characterization of neutrophil genome topology. Genes & Development
Bonora G, Plath K, Denholtz M. (2014) A mechanistic link between gene regulation and genome architecture in mammalian development. Current Opinion in Genetics & Development. 27: 92-101
Denholtz M, Bonora G, Chronis C, et al. (2013) Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell. 13: 602-16
Denholtz M, Plath K. (2012) Pluripotency in 3D: genome organization in pluripotent cells. Current Opinion in Cell Biology. 24: 793-801
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