Yuting Sun, Ph.D.

Affiliations: 
2009 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
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"Yuting Sun"

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Andrew Belmont grad student 2009 UIUC
 (Mechanisms of mTOR signal transduction regulating cell growth and differentiation.)
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Publications

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Sun Y, Meyers BA, Czako B, et al. (2020) Allosteric SHP2 inhibitor IACS-13909 overcomes EGFR-dependent and EGFR-independent resistance mechanisms towards osimertinib. Cancer Research
Zhang L, Yao Y, Zhang S, et al. (2019) Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma. Science Translational Medicine. 11
Echeverria GV, Ge Z, Seth S, et al. (2019) Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state. Science Translational Medicine. 11
Sun Y, Bandi M, Lofton T, et al. (2019) Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation. Cell Reports. 26: 469-482.e5
Echeverria G, Ge Z, Seth S, et al. (2019) Abstract GS5-05: Resistance to neoadjuvant chemotherapy in triple negative breast cancer mediated by a reversible drug-tolerant state Cancer Research. 79
Sun Y, Meyers BA, Johnson SB, et al. (2019) Abstract C036: Discovery of IACS-13909, an allosteric SHP2 inhibitor that overcomes multiple mechanisms underlying osimertinib resistance Molecular Cancer Therapeutics. 18
Molina JR, Sun Y, Protopopova M, et al. (2018) An inhibitor of oxidative phosphorylation exploits cancer vulnerability. Nature Medicine
Lissanu Deribe Y, Sun Y, Terranova C, et al. (2018) Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer. Nature Medicine
Zhang L, Zhang H, Guo H, et al. (2018) A Novel Patient-Derived Xenograft Model of Secondary CD20- CNS Lymphoma for Mechanistic and Therapeutic Exploration Blood. 132: 1669-1669
Marszalek JR, Seth S, Corti D, et al. (2018) Abstract 2856: Targeting OXPHOS with IACS-010759 to eliminate standard of care resistant tumor cells Cancer Research. 78: 2856-2856
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