Keith A. Wheaton, Ph.D.
Affiliations: | 2002 | University of Calgary, Calgary, Alberta, Canada |
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"Keith Wheaton"Parents
Sign in to add mentorKarl RIabowol | grad student | 2002 | University of Calgary | |
(Regulation of the serum response factor during cellular senescence of human fibroblasts.) |
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Publications
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Wheaton K, Campuzano D, Ma W, et al. (2017) Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson Gilford Progeria Syndrome. Molecular and Cellular Biology |
Wheaton K, Sarkari F, Stanly Johns B, et al. (2017) UbE2E1/UBCH6 is a critical in vivo E2 for the PRC1 catalyzed ubiquitination of H2A at K119. The Journal of Biological Chemistry |
Sarkari F, Wheaton K, La Delfa A, et al. (2013) Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. The Journal of Biological Chemistry. 288: 16975-85 |
Assaily W, Rubinger DA, Wheaton K, et al. (2011) ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress. Molecular Cell. 44: 491-501 |
Wheaton K. (2011) Caveolar vesicles generate DNA damage and perpetuate cellular aging. Cell Research. 21: 993-4 |
Wheaton K, Muir J, Ma W, et al. (2010) BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence. Aging Cell. 9: 747-60 |
Wheaton K, Riabowol K. (2004) Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factor. Molecular and Cellular Biology. 24: 7298-311 |
Wheaton K, Sampsel K, Boisvert FM, et al. (2001) Loss of functional caveolae during senescence of human fibroblasts. Journal of Cellular Physiology. 187: 226-35 |
Meyyappan M, Wheaton K, Riabowol KT. (1999) Decreased expression and activity of the immediate-early growth response (Egr-1) gene product during cellular senescence. Journal of Cellular Physiology. 179: 29-39 |
Wheaton K, Atadja P, Riabowol K. (1996) Regulation of transcription factor activity during cellular aging. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 74: 523-34 |