Keith A. Wheaton, Ph.D.

Affiliations: 
2002 University of Calgary, Calgary, Alberta, Canada 
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"Keith Wheaton"

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Karl RIabowol grad student 2002 University of Calgary
 (Regulation of the serum response factor during cellular senescence of human fibroblasts.)
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Wheaton K, Campuzano D, Ma W, et al. (2017) Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson Gilford Progeria Syndrome. Molecular and Cellular Biology
Wheaton K, Sarkari F, Stanly Johns B, et al. (2017) UbE2E1/UBCH6 is a critical in vivo E2 for the PRC1 catalyzed ubiquitination of H2A at K119. The Journal of Biological Chemistry
Sarkari F, Wheaton K, La Delfa A, et al. (2013) Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. The Journal of Biological Chemistry. 288: 16975-85
Assaily W, Rubinger DA, Wheaton K, et al. (2011) ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress. Molecular Cell. 44: 491-501
Wheaton K. (2011) Caveolar vesicles generate DNA damage and perpetuate cellular aging. Cell Research. 21: 993-4
Wheaton K, Muir J, Ma W, et al. (2010) BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence. Aging Cell. 9: 747-60
Wheaton K, Riabowol K. (2004) Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factor. Molecular and Cellular Biology. 24: 7298-311
Wheaton K, Sampsel K, Boisvert FM, et al. (2001) Loss of functional caveolae during senescence of human fibroblasts. Journal of Cellular Physiology. 187: 226-35
Meyyappan M, Wheaton K, Riabowol KT. (1999) Decreased expression and activity of the immediate-early growth response (Egr-1) gene product during cellular senescence. Journal of Cellular Physiology. 179: 29-39
Wheaton K, Atadja P, Riabowol K. (1996) Regulation of transcription factor activity during cellular aging. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 74: 523-34
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