Lindsay B. Case, Ph.D.

Affiliations: 
2014 Cell and Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cell motility, cytoskeleton
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"Lindsay Case"

Parents

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Omar A. Quintero research assistant
 (undergraduate researcher)
Clare Waterman grad student 2014 UNC Chapel Hill
 (Spatiotemporal coordination of the actin cytoskeleton and integrin adhesion.)
Michael K. Rosen post-doc (Chemistry Tree)
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Publications

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Cheng X, Ullo MF, Case LB. (2022) Reconstitution of Phase-Separated Signaling Clusters and Actin Polymerization on Supported Lipid Bilayers. Frontiers in Cell and Developmental Biology. 10: 932483
Case LB, De Pasquale M, Henry L, et al. (2022) Synergistic phase separation of two pathways promotes integrin clustering and nascent adhesion formation. Elife. 11
Case LB, Ditlev JA, Rosen MK. (2019) Regulation of Transmembrane Signaling by Phase Separation. Annual Review of Biophysics
Case LB, Zhang X, Ditlev JA, et al. (2019) Stoichiometry controls activity of phase-separated clusters of actin signaling proteins. Science (New York, N.Y.). 363: 1093-1097
Ditlev JA, Case LB, Rosen MK. (2018) Who's in and Who's Out-Compositional Control of Biomolecular Condensates. Journal of Molecular Biology
Campbell SL, Thompson PM, Ramachandran S, et al. (2017) Role of PIP2-Dependent Membrane Interactions in Vinculin Activation, Motility and Force Transmission Biophysical Journal. 112: 479a
Thompson PM, Ramachandran S, Case LB, et al. (2016) A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization. Structure (London, England : 1993)
Case LB, Waterman CM. (2015) Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch. Nature Cell Biology. 17: 955-63
Case LB, Baird MA, Shtengel G, et al. (2015) Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions. Nature Cell Biology. 17: 880-92
Pasapera AM, Plotnikov SV, Fischer RS, et al. (2015) Rac1-dependent phosphorylation and focal adhesion recruitment of myosin IIA regulates migration and mechanosensing. Current Biology : Cb. 25: 175-86
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