Xiangshu Xiao

Affiliations: 
Physiology and Pharmocology Oregon Health and Science University, Portland, OR 
Area:
Chemical biology, organic synthesis, medicinal chemistry
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"Xiangshu Xiao"
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Publications

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Xie F, Martin-Acosta P, Li BX, et al. (2020) Mechanistic Insights into the Activation of Ester Prodrugs of 666-15. Bioorganic & Medicinal Chemistry Letters. 127455
Meng Q, Li BX, Xiao X. (2018) Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics. Frontiers in Molecular Biosciences. 5: 35
Li BX, Chen J, Chao B, et al. (2018) Anticancer pyrroloquinazoline LBL1 targets nuclear lamins. Acs Chemical Biology
Xie F, Li BX, Kassenbrock A, et al. (2015) Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity. Journal of Medicinal Chemistry. 58: 5075-87
Chao B, Li BX, Xiao X. (2015) The chemistry and pharmacology of privileged pyrroloquinazolines. Medchemcomm. 6: 510-520
Li BX, Xie F, Fan Q, et al. (2014) Novel Type of Prodrug Activation through a Long-Range O,N-Acyl Transfer: A Case of Water-Soluble CREB Inhibitor. Acs Medicinal Chemistry Letters. 5: 1104-9
Chen J, Kassenbrock A, Li BX, et al. (2013) Discovery of a Potent Anti-tumor Agent through Regioselective Mono-N-acylation of 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine. Medchemcomm. 4: 1275-1282
Xie F, Li BX, Broussard C, et al. (2013) Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription. Bioorganic & Medicinal Chemistry Letters. 23: 5371-5
Mitton B, Dutta R, Hsu Y, et al. (2013) The pp90rsk-CREB Signaling Pathway Regulates Apoptosis In Acute Myelogenous Leukemia Blood. 122: 3801-3801
Xiao X, Li B, Xie F, et al. (2013) Abstract P4-15-08: Discovery of a potent inhibitor of CREB-mediated gene transcription that completely suppresses the growth of triple-negative breast cancer cells Cancer Research. 73
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