Jack A. Dunkle, Ph.D.

Affiliations: 
Chemistry & Biochemistry The University of Alabama, Tuscaloosa, AL 
 2010 Molecular & Cell Biology University of California, Berkeley, Berkeley, CA 
Area:
Molecular Basis for Protein Synthesis by the Ribosome
Website:
https://chemistry.ua.edu/faculty_profiles/jack-a-dunkle/
Google:
"Jack Dunkle"
Cross-listing: Chemistry Tree

Parents

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Jamie H.D. Cate grad student 2010 UC Berkeley
 (Structural Studies of the Elongation Cycle of Protein Synthesis and Its Inhibition by Antibiotics.)
Christine M. Dunham post-doc Emory (Chemistry Tree)
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Publications

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Dunkle JA, Bruno MR, Frantom PA. (2020) Structural evidence for a latch mechanism regulating access to the active site of SufS-family cysteine desulfurases. Acta Crystallographica. Section D, Structural Biology. 76: 291-301
Blahut M, Wise CE, Bruno MR, et al. (2019) Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues. The Journal of Biological Chemistry
Dunkle JA, Bruno M, Outten FW, et al. (2018) Structural evidence for dimer-interface driven regulation of the type II cysteine desulfurase, SufS. Biochemistry
Hong S, Sunita S, Maehigashi T, et al. (2018) Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proceedings of the National Academy of Sciences of the United States of America
Walker FC, Chou-Zheng L, Dunkle JA, et al. (2017) Molecular determinants for CRISPR RNA maturation in the Cas10-Csm complex and roles for non-Cas nucleases. Nucleic Acids Research. 45: 2112-2123
Hong S, Sunita S, Schureck MA, et al. (2017) Molecular mechanisms of translational control Acta Crystallographica Section a Foundations and Advances. 73: a431-a431
Schureck MA, Dunkle JA, Maehigashi T, et al. (2015) Defining the mRNA recognition signature of a bacterial toxin protein. Proceedings of the National Academy of Sciences of the United States of America. 112: 13862-7
Dunkle JA, Dunham CM. (2015) Mechanisms of mRNA frame maintenance and its subversion during translation of the genetic code. Biochimie. 114: 90-6
Fagan CE, Maehigashi T, Dunkle JA, et al. (2014) Structural insights into translational recoding by frameshift suppressor tRNASufJ. Rna (New York, N.Y.). 20: 1944-54
Maehigashi T, Dunkle JA, Miles SJ, et al. (2014) Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proceedings of the National Academy of Sciences of the United States of America. 111: 12740-5
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