Sadie Wignall, Ph.D.

Affiliations: 
1997-2003 University of California, Berkeley, Berkeley, CA 
 2004-2010 Stanford University, Palo Alto, CA 
 2011- Molecular Biosciences Northwestern University, Evanston, IL 
Area:
Spindle assembly and chromosome dynamics during oocyte meiosis
Website:
https://sites.northwestern.edu/wignall-lab/
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"Sadie Wignall"

Parents

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Rebecca Heald grad student 2003 UC Berkeley
 (Identification and characterization of proteins involved in spindle assembly in Xenopus egg extracts.)
Anne Villeneuve post-doc 2004-2010 Stanford
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Publications

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Wolff ID, Hollis JA, Wignall SM. (2022) Acentrosomal spindle assembly and maintenance in oocytes requires a kinesin-12 non-motor microtubule interaction domain. Molecular Biology of the Cell. mbcE22020056
Mendoza AD, Sue A, Antipova O, et al. (2022) Dynamic zinc fluxes regulate meiotic progression in Caenorhabditis elegans†. Biology of Reproduction
Cavin-Meza G, Kwan MM, Wignall SM. (2022) Multiple motors cooperate to establish and maintain acentrosomal spindle bipolarity in oocyte meiosis. Elife. 11
Divekar NS, Davis-Roca AC, Zhang L, et al. (2021) A degron-based strategy reveals new insights into Aurora B function in C. elegans. Plos Genetics. 17: e1009567
Hollis JA, Glover ML, Schlientz AJ, et al. (2020) Excess crossovers impede faithful meiotic chromosome segregation in C. elegans. Plos Genetics. 16: e1009001
Mullen TJ, Davis-Roca AC, Wignall SM. (2019) Spindle assembly and chromosome dynamics during oocyte meiosis. Current Opinion in Cell Biology. 60: 53-59
Heath CM, Wignall SM. (2019) Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis. Molecular Biology of the Cell. mbcE18100666
Davis-Roca AC, Divekar NS, Ng RK, et al. (2018) Dynamic SUMO remodeling drives a series of critical events during the meiotic divisions in C. elegans. Plos Genetics. 14: e1007626
Mullen TJ, Wignall SM. (2017) Interplay between microtubule bundling and sorting factors ensures acentriolar spindle stability during C. elegans oocyte meiosis. Plos Genetics. 13: e1006986
Davis-Roca AC, Muscat CC, Wignall SM. (2017) Caenorhabditis elegans oocytes detect meiotic errors in the absence of canonical end-on kinetochore attachments. The Journal of Cell Biology
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