John M. Sedivy

Molecular Biology, Cell Biology and Biochemistry Brown University, Providence, RI 
"John Michael Sedivy"


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Dan Gabriel Fraenkel grad student 1985 Harvard (Microtree)
 (Regulation of fructose-1, 6-bisphosphatase activity : a mutational analysis.)
Phillip Allen Sharp post-doc 1984-1988 MIT


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Maria K. Mateyak grad student 2001 Brown
Wenyi Wei grad student 2002 Brown
Brenda C. O'Connell grad student 2004 Brown
Shan Wei grad student 2005 Brown
Isil Guney grad student 2006 Brown
Wendy A. Jobling grad student 2006 Brown
Pooja Agrawal grad student 2007 Brown
Amy H. Whiting grad student 2007 Brown
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Taylor JR, Wood JG, Mizerak E, et al. (2022) Sirt6 regulates lifespan in . Proceedings of the National Academy of Sciences of the United States of America. 119
Gorgoulis V, Adams PD, Alimonti A, et al. (2019) Cellular Senescence: Defining a Path Forward. Cell. 179: 813-827
Zhao X, Petrashen AP, Sanders JA, et al. (2019) SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. Aging Cell. e12947
Ito T, Teo YV, Evans SA, et al. (2018) Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways. Cell Reports. 22: 3480-3492
Sarosiek KA, Fraser C, Muthalagu N, et al. (2016) Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics. Cancer Cell
Bacalini MG, Deelen J, Pirazzini C, et al. (2016) Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences
Criscione SW, De Cecco M, Siranosian B, et al. (2016) Reorganization of chromosome architecture in replicative cellular senescence. Science Advances. 2: e1500882
Gravina S, Sedivy JM, Vijg J. (2016) The dark side of circulating nucleic acids. Aging Cell
Waaijer ME, Croco E, Westendorp RG, et al. (2016) DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age. Aging
Borghesan M, Fusilli C, Rappa F, et al. (2016) DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression. Cancer Research
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