Brenda C. O'Connell, Ph.D.

2004 Brown University, Providence, RI 
"Brenda O'Connell"


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John M. Sedivy grad student 2004 Brown
 (Analysis of c-Myc-mediated G1 progression and identification of c-Myc target genes.)
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O'Connell BC, Adamson B, Lydeard JR, et al. (2010) A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability Molecular Cell. 40: 645-657
Acosta JC, Ferrándiz N, Bretones G, et al. (2008) Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest. Molecular and Cellular Biology. 28: 7286-95
Szlávik V, Vág J, Markó K, et al. (2008) Matrigel-induced acinar differentiation is followed by apoptosis in HSG cells Journal of Cellular Biochemistry. 103: 284-295
Remondini D, O'Connell B, Intrator N, et al. (2005) Targeting c-Myc-activated genes with a correlation method: detection of global changes in large gene expression network dynamics. Proceedings of the National Academy of Sciences of the United States of America. 102: 6902-6
Smith KP, Byron M, O'Connell BC, et al. (2004) c-Myc localization within the nucleus: evidence for association with the PML nuclear body. Journal of Cellular Biochemistry. 93: 1282-96
O'Connell BC, Cheung AF, Simkevich CP, et al. (2003) A large scale genetic analysis of c-Myc-regulated gene expression patterns. The Journal of Biological Chemistry. 278: 12563-73
Nikiforov MA, Chandriani S, O'Connell B, et al. (2002) A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism. Molecular and Cellular Biology. 22: 5793-800
Zheng C, Hoque ATMS, Braddon VR, et al. (2001) Evaluation of salivary gland acinar and ductal cell-specific promoters in vivo with recombinant adenoviral vectors Human Gene Therapy. 12: 2215-2223
Jung DW, Hecht D, Ho SW, et al. (2000) PKC and ERK1/2 regulate amylase promoter activity during differentiation of a salivary gland cell line Journal of Cellular Physiology. 185: 215-225
Hermeking H, Rago C, Schuhmacher M, et al. (2000) Identification of CDK4 as a target of c-MYC. Proceedings of the National Academy of Sciences of the United States of America. 97: 2229-34
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