Jeffry D. Sander, Ph.D.

Affiliations: 
2008 Genetics, Development and Cell Biology Iowa State University, Ames, IA, United States 
Area:
Bioinformatics Biology
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"Jeffry Sander"

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Daniel F. Voytas grad student 2008 Iowa State
 (Characterization and design of C2H2 zinc finger proteins as custom DNA binding domains.)
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Publications

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Tak YE, Boulay G, Lee L, et al. (2022) Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors. Cell Genomics. 2
Gao H, Mutti J, Young JK, et al. (2020) Complex Trait Loci in Maize Enabled by CRISPR-Cas9 Mediated Gene Insertion. Frontiers in Plant Science. 11: 535
Hubbard BP, Badran AH, Zuris JA, et al. (2015) Continuous directed evolution of DNA-binding proteins to improve TALEN specificity. Nature Methods. 12: 939-42
Rogers JM, Barrera LA, Reyon D, et al. (2015) Context influences on TALE-DNA binding revealed by quantitative profiling. Nature Communications. 6: 7440
Gjini E, Mansour MR, Sander JD, et al. (2015) A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Molecular and Cellular Biology. 35: 789-804
Gjini E, Mansour M, Sander J, et al. (2015) Abstract 5152: Zebrafish models of myeloid malignancies produced through tet2 and asxl1 genomic editing Cancer Research. 75: 5152-5152
Sander JD, Joung JK. (2014) CRISPR-Cas systems for editing, regulating and targeting genomes. Nature Biotechnology. 32: 347-55
Guilinger JP, Pattanayak V, Reyon D, et al. (2014) Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity Nature Methods. 11: 429-435
Fu Y, Sander JD, Reyon D, et al. (2014) Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Nature Biotechnology. 32: 279-84
Maeder ML, Angstman JF, Richardson ME, et al. (2013) Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. Nature Biotechnology. 31: 1137-42
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