Alec W. Gross, Ph.D.

Affiliations: 
2002 Brandeis University, Waltham, MA, United States 
Area:
Oncology, Cell Biology, Genetics
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"Alec Gross"

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Ruibao Ren grad student 2002 Brandeis
 (Dissecting molecular mechanisms of leukemogenesis with a mouse chronic myelogenous leukemia model.)
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Publications

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Jin H, D'Urso V, Neuteboom B, et al. (2021) Avelumab internalization by human circulating immune cells is mediated by both Fc gamma receptor and PD-L1 binding. Oncoimmunology. 10: 1958590
Dietrich S, Gross AW, Becker S, et al. (2019) Constant domain-exchanged Fab enables specific light chain pairing in heterodimeric bispecific SEED-antibodies. Biochimica Et Biophysica Acta. Proteins and Proteomics
Newhouse TR, Kaib PS, Gross AW, et al. (2013) Versatile approaches for the synthesis of fused-ring γ-lactones utilizing cyclopropane intermediates. Organic Letters. 15: 1591-3
Gross AW, Dawson JP, Muda M, et al. (2013) Strand Exchange Engineered Domain (Seed): A Novel Platform Designed to Generate Mono and Multispecific Protein Therapeutics Fusion Protein Technologies For Biopharmaceuticals: Applications and Challenges. 557-569
Kelton C, Wesolowski JS, Soloviev M, et al. (2012) Anti-EGFR biparatopic-SEED antibody has enhanced combination-activity in a single molecule. Archives of Biochemistry and Biophysics. 526: 219-25
Muda M, Gross AW, Dawson JP, et al. (2011) Therapeutic assessment of SEED: a new engineered antibody platform designed to generate mono- and bispecific antibodies. Protein Engineering, Design & Selection : Peds. 24: 447-54
Zhang YL, Radhakrishnan ML, Lu X, et al. (2009) Symmetric signaling by an asymmetric 1 erythropoietin: 2 erythropoietin receptor complex. Molecular Cell. 33: 266-74
Aderinto J, Gross AW, Rittenhouse B. (2009) Non-traumatic anterior dislocation of a total knee replacement associated with neurovascular injury Annals of the Royal College of Surgeons of England. 91: 658-659
Boyd MA, Gross AW, Hope K, et al. (2009) 3CE modeling & simulation environment reuse for test and evaluation Fall Simulation Interoperability Workshop 2009, 2009 Fall Siw. 285-292
Um M, Gross AW, Lodish HF. (2007) A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells. Cellular Signalling. 19: 634-45
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