Taj D. King, Ph.D.

Affiliations: 
2005 University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Cell Biology
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"Taj King"

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Richard S. Jope grad student 2005 UAB
 (Signaling pathways regulating cell survival: Oxidative stress and glycogen synthase kinase-3 (GSK3).)
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Publications

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Lu W, Lin C, King TD, et al. (2012) Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells. Cellular Signalling. 24: 2291-6
King TD, Zhang W, Suto MJ, et al. (2012) Frizzled7 as an emerging target for cancer therapy. Cellular Signalling. 24: 846-51
King TD, Suto MJ, Li Y. (2012) The Wnt/β-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer. Journal of Cellular Biochemistry. 113: 13-8
Li Y, Lu W, King TD, et al. (2010) Dkk1 stabilizes Wnt co-receptor LRP6: implication for Wnt ligand-induced LRP6 down-regulation. Plos One. 5: e11014
King TD, Clodfelder-Miller B, Barksdale KA, et al. (2008) Unregulated mitochondrial GSK3beta activity results in NADH: ubiquinone oxidoreductase deficiency. Neurotoxicity Research. 14: 367-82
King TD, Gandy JC, Bijur GN. (2006) The protein phosphatase-1/inhibitor-2 complex differentially regulates GSK3 dephosphorylation and increases sarcoplasmic/endoplasmic reticulum calcium ATPase 2 levels. Experimental Cell Research. 312: 3693-700
King TD, Song L, Jope RS. (2006) AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3. Biochemical Pharmacology. 71: 1637-47
King TD, Jope RS. (2005) Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress. Neuroreport. 16: 597-601
De Sarno P, Shestopal SA, King TD, et al. (2003) Muscarinic receptor activation protects cells from apoptotic effects of DNA damage, oxidative stress, and mitochondrial inhibition. The Journal of Biological Chemistry. 278: 11086-93
King TD, Bijur GN, Jope RS. (2001) Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium. Brain Research. 919: 106-14
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