Christopher J. Yuskaitis, Ph.D.

Affiliations: 
2009 Cell Biology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Neuroscience Biology
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"Christopher Yuskaitis"

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Richard S. Jope grad student 2009 UAB
 (Neuroinflammation and Fragile X syndrome: Regulation by glycogen synthase kinase-3.)
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Publications

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Yuskaitis CJ, Rossitto LA, Gurnani S, et al. (2019) Chronic mTORC1 inhibition rescues behavioral and biochemical deficits resulting from neuronal Depdc5 loss in mice. Human Molecular Genetics
Trowbridge SK, Yuskaitis CJ, Baumer N, et al. (2019) Brain MRI abnormalities in patients with infantile spasms and Down syndrome. Epilepsy & Behavior : E&B. 92: 57-60
Yuskaitis CJ, Jones BM, Wolfson RL, et al. (2017) A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility. Neurobiology of Disease
Winden KD, Yuskaitis CJ, Poduri A. (2015) Megalencephaly and Macrocephaly. Seminars in Neurology. 35: 277-87
Poduri A, Heinzen EL, Chitsazzadeh V, et al. (2013) SLC25A22 is a novel gene for migrating partial seizures in infancy. Annals of Neurology. 74: 873-82
Yuskaitis CJ, Beurel E, Jope RS. (2010) Evidence of reactive astrocytes but not peripheral immune system activation in a mouse model of Fragile X syndrome. Biochimica Et Biophysica Acta. 1802: 1006-12
Mines MA, Yuskaitis CJ, King MK, et al. (2010) GSK3 influences social preference and anxiety-related behaviors during social interaction in a mouse model of fragile X syndrome and autism. Plos One. 5: e9706
Yuskaitis CJ, Mines MA, King MK, et al. (2010) Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome. Biochemical Pharmacology. 79: 632-46
Yuskaitis CJ, Jope RS. (2009) Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity. Cellular Signalling. 21: 264-73
Min WW, Yuskaitis CJ, Yan Q, et al. (2009) Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential. Neuropharmacology. 56: 463-72
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