Jennifer F. Garcia, Ph.D.

Affiliations: 
2012 Biochemistry and Molecular Biology University of California, San Francisco, San Francisco, CA 
Area:
Genetics, Molecular Biology
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"Jennifer Garcia"

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Hiten Madhani grad student 2012 UCSF
 (Closing the gaps and pushing the boundaries: Understanding the mechanism and regulation of heterochromatin-induced transcriptional silencing.)
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Publications

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Roth R, Madhani HD, Garcia JF. (2018) Total RNA Isolation and Quantification of Specific RNAs in Fission Yeast. Methods in Molecular Biology (Clifton, N.J.). 1721: 63-72
Garcia JF, Al-Sady B, Madhani HD. (2015) Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe. G3 (Bethesda, Md.). 5: 1453-61
Canzio D, Liao M, Naber N, et al. (2013) A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature. 496: 377-81
Canzio D, Liang M, Naber N, et al. (2013) Abstract IA23: Functional and structural studies of HP1 heterochromatin Cancer Research. 73
Rougemaille M, Braun S, Coyle S, et al. (2012) Ers1 links HP1 to RNAi. Proceedings of the National Academy of Sciences of the United States of America. 109: 11258-63
Kiely CM, Marguerat S, Garcia JF, et al. (2011) Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe. Molecular and Cellular Biology. 31: 4193-204
Braun S, Garcia JF, Rowley M, et al. (2011) The Cul4-Ddb1(Cdt)² ubiquitin ligase inhibits invasion of a boundary-associated antisilencing factor into heterochromatin. Cell. 144: 41-54
Garcia JF, Dumesic PA, Hartley PD, et al. (2010) Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions. Genes & Development. 24: 1758-71
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