Cynthia A. Luppen, Ph.D.

Affiliations: 
2005 University of Southern California, Los Angeles, CA, United States 
Area:
Biochemistry, Molecular Biology
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"Cynthia Luppen"

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Baruch Frenkel grad student 2005 USC
 (Anti-glucocorticoid actions of bone morphogenetic protein-2 in osteoblasts.)
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Publications

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Chan CK, Lindau P, Jiang W, et al. (2013) Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12643-8
Chan CK, Chen CC, Luppen CA, et al. (2009) Endochondral ossification is required for haematopoietic stem-cell niche formation. Nature. 457: 490-4
Luppen CA, Chandler RL, Noh T, et al. (2008) BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization. Growth Factors (Chur, Switzerland). 26: 226-37
Kim JB, Leucht P, Lam K, et al. (2007) Bone regeneration is regulated by wnt signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1913-23
Kim JB, Leucht P, Luppen CA, et al. (2007) Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration. Bone. 41: 39-51
Kim JB, Leucht P, Lam K, et al. (2006) Wnt signaling is essential for bone regeneration McB Molecular and Cellular Biomechanics. 3: 201
Leclerc N, Luppen CA, Ho VV, et al. (2004) Gene expression profiling of glucocorticoid-inhibited osteoblasts. Journal of Molecular Endocrinology. 33: 175-93
Luppen CA, Leclerc N, Noh T, et al. (2003) Brief bone morphogenetic protein 2 treatment of glucocorticoid-inhibited MC3T3-E1 osteoblasts rescues commitment-associated cell cycle and mineralization without alteration of Runx2. The Journal of Biological Chemistry. 278: 44995-5003
Luppen CA, Smith E, Spevak L, et al. (2003) Bone morphogenetic protein-2 restores mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 1186-97
Luppen CA, Blake CA, Ammirati KM, et al. (2002) Recombinant human bone morphogenetic protein-2 enhances osteotomy healing in glucocorticoid-treated rabbits. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 301-10
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