E Premkumar Reddy

Molecular Biology and Genetics Temple University, Philadelphia, PA, United States 
Molecular Biology
"E Reddy"
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Baker SJ, Cosenza SC, Athuluri-Divakar S, et al. (2020) A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding Agent. Molecular Cell. 79: 180-190.e4
Padgaonkar A, Rechkoblit O, Vasquez-Del Carpio R, et al. (2018) Targeting protein kinase CK2 and CDK4/6 pathways with a multi-kinase inhibitor ON108110 suppresses pro-survival signaling and growth in mantle cell lymphoma and T-acute lymphoblastic leukemia. Oncotarget. 9: 37753-37765
Dhanasekaran DN, Reddy EP. (2017) JNK-signaling: A multiplexing hub in programmed cell death. Genes & Cancer. 8: 682-694
Ha JH, Yan M, Gomathinayagam R, et al. (2016) Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer. Oncotarget
Athuluri-Divakar SK, Vasquez-Del Carpio R, Dutta K, et al. (2016) A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling. Cell. 165: 643-655
Perumal D, Kuo PY, Leshchenko VV, et al. (2016) Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma. Cancer Research
Reddy MV, Akula B, Jatiani S, et al. (2015) Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2). Bioorganic & Medicinal Chemistry
Ramkumar P, Lee CM, Moradian A, et al. (2015) JNK associated leucine zipper protein functions as a docking platform for Polo like kinase 1 and regulation of the associating transcription factor Forkhead box protein K1. The Journal of Biological Chemistry
Eachkoti R, Reddy MV, Lieu YK, et al. (2014) Identification and characterisation of a novel heat shock protein 90 inhibitor ONO4140. European Journal of Cancer (Oxford, England : 1990). 50: 1982-92
Agoni L, Basu I, Gupta S, et al. (2014) Rigosertib is a more effective radiosensitizer than cisplatin in concurrent chemoradiation treatment of cervical carcinoma, in vitro and in vivo. International Journal of Radiation Oncology, Biology, Physics. 88: 1180-7
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