Kimberly A. Loesch, Ph.D.
Affiliations: | 2006 | University of Alabama, Birmingham, Birmingham, AL, United States |
Area:
Cell BiologyGoogle:
"Kimberly Loesch"Parents
Sign in to add mentor| Stuart J. Frank | grad student | 2006 | UAB | |
| (Mechanism and regulation of growth hormone receptor proteolysis and shedding.) | ||||
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Publications
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| Crespo RA, Dang Q, Zhou NE, et al. (2019) Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. Journal of Medicinal Chemistry |
| Craig JK, Risler JK, Loesch KA, et al. (2016) Mycobacterium Cytidylate Kinase Appears to Be an Undruggable Target. Journal of Biomolecular Screening |
| Zhang Y, Wang X, Loesch K, et al. (2016) Tissue Inhibitor of Metalloproteinases 3 (TIMP3) Modulates Growth Hormone Receptor (GHR) Susceptibility to Inducible Proteolysis and Cellular Growth Hormone (GH) Sensitivity. Molecular Endocrinology (Baltimore, Md.). me20151302 |
| Cescato R, Loesch KA, Waser B, et al. (2010) Agonist-biased signaling at the sst2A receptor: the multi-somatostatin analogs KE108 and SOM230 activate and antagonize distinct signaling pathways. Molecular Endocrinology (Baltimore, Md.). 24: 240-9 |
| Loesch K, Deng L, Wang X, et al. (2007) Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells. Endocrinology. 148: 5955-65 |
| Asa SL, Digiovanni R, Jiang J, et al. (2007) A growth hormone receptor mutation impairs growth hormone autofeedback signaling in pituitary tumors. Cancer Research. 67: 7505-11 |
| Han X, Benight N, Osuntokun B, et al. (2007) Tumour necrosis factor α blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis Gut. 56: 73-81 |
| Han X, Osuntokun B, Benight N, et al. (2006) Signal transducer and activator of transcription 5b promotes mucosal tolerance in pediatric Crohn's disease and murine colitis. The American Journal of Pathology. 169: 1999-2013 |
| Loesch K, Deng L, Cowan JW, et al. (2006) Janus kinase 2 influences growth hormone receptor metalloproteolysis. Endocrinology. 147: 2839-49 |
| He K, Loesch K, Cowan JW, et al. (2005) Janus kinase 2 enhances the stability of the mature growth hormone receptor. Endocrinology. 146: 4755-65 |