Jason W. Upton, Ph.D.
Affiliations: | 2006 | Washington University, Saint Louis, St. Louis, MO |
Area:
Virology Biology, Cell BiologyGoogle:
"Jason Upton"Parents
Sign in to add mentor| Helen Piwnica-Worms | grad student | 2006 | Washington University | |
| (Characterization of the murine gammaherpesvirus-68 viral cyclin and its role in regulating reactivation from latency.) | ||||
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Publications
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| Yadav SK, Gawargi FI, Hasan MH, et al. (2023) Differential effects of CMV infection on the viability of cardiac cells. Cell Death Discovery. 9: 111 |
| Koehler H, Cotsmire S, Zhang T, et al. (2021) Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis. Cell Host & Microbe |
| Lane RK, Guo H, Fisher AD, et al. (2020) Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America |
| Zhang T, Yin C, Boyd DF, et al. (2020) Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis. Cell. 180: 1115-1129.e13 |
| Upton JW, Kaiser WJ, Mocarski ES. (2019) DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA. Cell Host & Microbe. 26: 564 |
| Guo H, Gilley RP, Fisher A, et al. (2018) Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1. Cell Death & Disease. 9: 816 |
| Gopal S, Perez E, Xia AY, et al. (2018) Murine cytomegalovirus M72 promotes acute virus replication in vivo and is a substrate of the TRiC/CCT complex. Virology. 522: 92-105 |
| Koehler H, Cotsmire S, Langland J, et al. (2017) Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3. Proceedings of the National Academy of Sciences of the United States of America. 114: 11506-11511 |
| Maelfait J, Liverpool L, Bridgeman A, et al. (2017) Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis. The Embo Journal |
| Sridharan H, Ragan KB, Guo H, et al. (2017) Murine cytomegalovirus IE3-dependent transcription is required for DAI/ZBP1-mediated necroptosis. Embo Reports |