Venugopal Bhaskara, Ph.D.

Affiliations: 
2006 Chemistry and Biochemistry University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Mechanical Engineering
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"Venugopal Bhaskara"

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Tanya T. Paull grad student 2006 UT Austin
 (Investigation of the mechanistic basis for the role of Rad50 in double -strand break repair.)
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Publications

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Huis in 't Veld PJ, Herzog F, Ladurner R, et al. (2014) Characterization of a DNA exit gate in the human cohesin ring. Science (New York, N.Y.). 346: 968-72
Ladurner R, Bhaskara V, Huis in 't Veld PJ, et al. (2014) Cohesin's ATPase activity couples cohesin loading onto DNA with Smc3 acetylation. Current Biology : Cb. 24: 2228-37
Tedeschi A, Wutz G, Huet S, et al. (2013) Wapl is an essential regulator of chromatin structure and chromosome segregation. Nature. 501: 564-8
Nishiyama T, Ladurner R, Schmitz J, et al. (2010) Sororin mediates sister chromatid cohesion by antagonizing Wapl. Cell. 143: 737-49
Peters JM, Bhaskara V. (2009) Cohesin acetylation: from antiestablishment to establishment. Molecular Cell. 34: 1-2
Lengsfeld BM, Rattray AJ, Bhaskara V, et al. (2007) Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Molecular Cell. 28: 638-51
Bhaskara V, Dupré A, Lengsfeld B, et al. (2007) Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes. Molecular Cell. 25: 647-61
Moncalian G, Lengsfeld B, Bhaskara V, et al. (2004) The rad50 signature motif: essential to ATP binding and biological function. Journal of Molecular Biology. 335: 937-51
Lee JH, Ghirlando R, Bhaskara V, et al. (2003) Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes. The Journal of Biological Chemistry. 278: 45171-81
Zot HG, Bhaskara V, Liu L. (2000) Acan125 binding to the SH3 domain of acanthamoeba myosin-IC Archives of Biochemistry and Biophysics. 375: 161-164
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