James K. Mangan, Ph.D.

Affiliations: 
2005 Temple University, Philadelphia, PA, United States 
Area:
Molecular Biology, Immunology
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"James Mangan"

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E Premkumar Reddy grad student 2005 Temple University
 (Molecular mechanisms associated with upregulation of Jak3 transcription during myeloid differentiation.)
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Publications

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Hexner EO, Luger SM, Reshef R, et al. (2016) Infusion of CD3/CD28 co-stimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment. American Journal of Hematology
Reshef R, Huffman AP, Gao A, et al. (2015) High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Bagley SJ, Sehgal AR, Gill S, et al. (2015) Acute cholecystitis is a common complication after allogeneic stem cell transplantation and is associated with the use of total parenteral nutrition. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 21: 768-71
Reshef R, Hexner EO, Loren AW, et al. (2014) Early donor chimerism levels predict relapse and survival after allogeneic stem cell transplantation with reduced-intensity conditioning. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 1758-66
Diab A, Zickl L, Abdel-Wahab O, et al. (2013) Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis. Leukemia Research. 37: 32-6
Mangan JK, Speck NA. (2011) RUNX1 mutations in clonal myeloid disorders: from conventional cytogenetics to next generation sequencing, a story 40 years in the making. Critical Reviews in Oncogenesis. 16: 77-91
Cai X, Gaudet JJ, Mangan JK, et al. (2011) Runx1 loss minimally impacts long-term hematopoietic stem cells. Plos One. 6: e28430
Mangan JK, Russell JE. (2009) Profound neutropenia resulting from metyrapone-induced adrenal crisis. American Journal of Hematology. 84: 773
Mangan JK, Tantravahi RV, Rane SG, et al. (2006) Granulocyte colony-stimulating factor-induced upregulation of Jak3 transcription during granulocytic differentiation is mediated by the cooperative action of Sp1 and Stat3. Oncogene. 25: 2489-99
Mangan JK, Reddy EP. (2005) Activation of the Jak3 pathway and myeloid differentiation. Leukemia & Lymphoma. 46: 21-7
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