Brian D. Beck, Ph.D.

2008 Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Molecular Biology
"Brian Beck"


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Suk-Hee Lee grad student 2008 Indiana University
 (Functional analysis of two novel DNA repair factors, Metnase and Pso4.)
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Hromas R, Williamson EA, Fnu S, et al. (2012) Chk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restart. Oncogene. 31: 4245-54
Park SJ, Beck BD, Saadatzadeh MR, et al. (2011) Fanconi anemia D2 protein is an apoptotic target mediated by caspases. Journal of Cellular Biochemistry. 112: 2383-91
Beck BD, Lee SS, Williamson E, et al. (2011) Biochemical characterization of metnase's endonuclease activity and its role in NHEJ repair. Biochemistry. 50: 4360-70
Beck BD, Lee SS, Hromas R, et al. (2010) Regulation of Metnase's TIR binding activity by its binding partner, Pso4. Archives of Biochemistry and Biophysics. 498: 89-94
Wray J, Williamson EA, Royce M, et al. (2009) Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells. Plos One. 4: e5323
Beck BD, Hah DS, Lee SH. (2008) XPB and XPD between transcription and DNA repair. Advances in Experimental Medicine and Biology. 637: 39-46
Williamson EA, Rasila KK, Corwin LK, et al. (2008) The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation. Nucleic Acids Research. 36: 5822-31
Beck BD, Park SJ, Lee YJ, et al. (2008) Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair. The Journal of Biological Chemistry. 283: 9023-30
Park SJ, Lee YJ, Beck BD, et al. (2006) A positive involvement of RecQL4 in UV-induced S-phase arrest. Dna and Cell Biology. 25: 696-703
Park SJ, Ciccone SL, Beck BD, et al. (2004) Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. The Journal of Biological Chemistry. 279: 30053-9
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