Fathima R. Kona, Ph.D.

Affiliations: 
2008 Biochemistry and Molecular Biology Wayne State University, Detroit, MI, United States 
Area:
Biochemistry, Molecular Biology
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"Fathima Kona"

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Domenico L. Gatti grad student 2008 Wayne State
 (Structure-function studies of Aquifex aeolicus 3-deoxy-D-manno-octulosonate 8-phosphate (KDO8P) synthase.)
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Publications

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Buac D, Kona FR, Seth AK, et al. (2013) Regulation of metformin response by breast cancer associated gene 2. Neoplasia (New York, N.Y.). 15: 1379-90
Kona FR, Stark K, Bisoski L, et al. (2011) Abstract 4035: The breast cancer associated gene 2 (BCA2) binds to Ubc9 and is involved in sumoylation Cancer Research. 71: 4035-4035
Burger AM, Kona F, Amemiya Y, et al. (2010) Role of the BCA2 ubiquitin E3 ligase in hormone responsive breast cancer. The Open Cancer Journal. 3: 116-123
Brahemi G, Kona FR, Fiasella A, et al. (2010) Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer. Journal of Medicinal Chemistry. 53: 2757-65
Kona FR, Bacopulos S, Amemiya Y, et al. (2010) Abstract 4599: The RING E3 ligase BCA2 is regulated by estrogen and co-expressed with estrogen receptor in breast cancer cells Cancer Research. 70: 4599-4599
Kona F, Tao P, Martin P, et al. (2009) Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry. 48: 3610-30
Kona F, Xu X, Martin P, et al. (2007) Structural and mechanistic changes along an engineered path from metallo to nonmetallo 3-deoxy-D-manno-octulosonate 8-phosphate synthases. Biochemistry. 46: 4532-44
Xu X, Kona F, Wang J, et al. (2005) The catalytic and conformational cycle of Aquifex aeolicus KDO8P synthase: role of the L7 loop. Biochemistry. 44: 12434-44
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