William F. Bosron

Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Molecular Biology, Biochemistry
"William Bosron"
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Edenberg HJ, Bosron WF. (2014) Alcohol Dehydrogenases Reference Module in Biomedical Research
Marrs JA, Clendenon SG, Ratcliffe DR, et al. (2010) Zebrafish fetal alcohol syndrome model: effects of ethanol are rescued by retinoic acid supplement. Alcohol (Fayetteville, N.Y.). 44: 707-15
Sanghani SP, Sanghani PC, Schiel MA, et al. (2009) Human carboxylesterases: an update on CES1, CES2 and CES3. Protein and Peptide Letters. 16: 1207-14
Mello T, Nakatsuka A, Fears S, et al. (2008) Expression of carboxylesterase and lipase genes in rat liver cell-types. Biochemical and Biophysical Research Communications. 374: 460-4
Janecki DJ, Bemis KG, Tegeler TJ, et al. (2007) A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme. Analytical Biochemistry. 369: 18-26
Schiel MA, Green SL, Davis WI, et al. (2007) Expression and characterization of a human carboxylesterase 2 splice variant. The Journal of Pharmacology and Experimental Therapeutics. 323: 94-101
Quinney SK, Sanghani SP, Davis WI, et al. (2005) Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide. The Journal of Pharmacology and Experimental Therapeutics. 313: 1011-6
Sanghani SP, Quinney SK, Fredenburg TB, et al. (2004) Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 505-11
Sun Z, Murry DJ, Sanghani SP, et al. (2004) Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1. The Journal of Pharmacology and Experimental Therapeutics. 310: 469-76
Sanghani SP, Quinney SK, Fredenburg TB, et al. (2003) Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4983-91
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