Channing J. Der
Affiliations: | Genetics & Molecular Biology | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Molecular Biology, Cell BiologyWebsite:
https://unclineberger.org/people/profiles/channing-j.-derGoogle:
"Channing J. Der"Bio:
https://www.ous-research.no/home/institute/news/16792
https://books.google.com/books?id=R7IvAQAAIAAJ
Parents
Sign in to add mentorEric J. Stanbridge | grad student | 1981 | UC Irvine (Chemistry Tree) | |
(Cell surface alterations associated with transformation and tumorgenicity in human cells.) | ||||
Geoffrey M. Cooper | post-doc | 1982 | Harvard Medical School (Chemistry Tree) |
Children
Sign in to add traineeIrem Ozkan-Dagliyan | grad student | University of North Carolina at Chapel Hill School of Medicine (Chemistry Tree) | |
Kevin Pruitt | grad student | 2001 | UNC Chapel Hill |
John M. Lambert | grad student | 2002 | UNC Chapel Hill |
Patricia A. Solski | grad student | 2003 | UNC Chapel Hill |
Aylin S. Ulku | grad student | 2003 | UNC Chapel Hill |
Emily J. Chenette | grad student | 2004 | UNC Chapel Hill |
Todd Palmby | grad student | 2004 | UNC Chapel Hill |
Jiyoung Cha | grad student | 2007 | UNC Chapel Hill |
Patrick J. Roberts | grad student | 2007 | UNC Chapel Hill |
Ariella B. Hanker | grad student | 2009 | UNC Chapel Hill |
Tanya P. Zand | grad student | 2010 | UNC Chapel Hill |
Danielle R. Cook | grad student | 2013 | UNC Chapel Hill |
Gary W. Reuther | post-doc | UNC Chapel Hill |
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Publications
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Schaefer A, Der CJ. (2022) RHOA takes the RHOad less traveled to cancer. Trends in Cancer |
Diehl JN, Hibshman PS, Ozkan-Dagliyan I, et al. (2021) Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer. Advances in Cancer Research. 153: 101-130 |
Cook DR, Kang M, Martin TD, et al. (2021) Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth. Cancer Research |
Diehl JN, Klomp JE, Snare KR, et al. (2021) The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer. The Journal of Biological Chemistry. 101335 |
Cox AD, Der CJ. (2021) Filling in the GAPs in understanding RAS. Science (New York, N.Y.). 374: 152-153 |
Waters AM, Der CJ. (2021) Validation of Isoform- and Mutation-Specific RAS Antibodies. Methods in Molecular Biology (Clifton, N.J.). 2262: 91-103 |
Klomp JE, Klomp JA, Der CJ. (2021) The ERK mitogen-activated protein kinase signaling network: the final frontier in RAS signal transduction. Biochemical Society Transactions |
Hodge RG, Schaefer A, Howard SV, et al. (2020) RAS and RHO family GTPase mutations in cancer: twin sons of different mothers? Critical Reviews in Biochemistry and Molecular Biology. 55: 386-407 |
Tew BY, Durand JK, Bryant KL, et al. (2020) Genome-wide DNA methylation analysis of KRAS mutant cell lines. Scientific Reports. 10: 10149 |
Escobar-Hoyos LF, Penson A, Kannan R, et al. (2020) Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer. Cancer Cell |