Mignon A. Keaton, Ph.D.

Affiliations: 
2007 Duke University, Durham, NC 
Area:
Molecular Biology, Cell Biology
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"Mignon Keaton"

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Daniel Lew grad student 2007 Duke
 (Characterization of Swe1p substrate specificity and subcellular localization.)
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Publications

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Im JS, Keaton M, Lee KY, et al. (2014) ATR checkpoint kinase and CRL1βTRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks. Genes & Development. 28: 875-87
Liu S, Miriyala S, Keaton MA, et al. (2014) Metabolic effects of acute thiamine depletion are reversed by rapamycin in breast and leukemia cells. Plos One. 9: e85702
Abbas T, Keaton M, Dutta A. (2013) Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2. Cell Cycle (Georgetown, Tex.). 12: 2175-82
Abbas T, Mueller AC, Shibata E, et al. (2013) CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration. Molecular Cell. 49: 1147-58
Abbas T, Keaton MA, Dutta A. (2013) Genomic instability in cancer. Cold Spring Harbor Perspectives in Biology. 5: a012914
Solmonson A, Keaton M, Nowinski SM, et al. (2013) Abstract 1888: Metabolomic analysis provides insights into uncoupling-induced cancer resistance in the K5-UCP3 mouse model. Cancer Research. 73: 1888-1888
Keaton MA, Dutta A. (2011) Rad18 emerges as a critical regulator of the Fanconi anemia pathway. Cell Cycle (Georgetown, Tex.). 10: 2414-5
Keaton MA, Taylor CM, Layer RM, et al. (2011) Nuclear scaffold attachment sites within ENCODE regions associate with actively transcribed genes. Plos One. 6: e17912
Crutchley J, King KM, Keaton MA, et al. (2009) Molecular dissection of the checkpoint kinase Hsl1p. Molecular Biology of the Cell. 20: 1926-36
Keaton MA, Szkotnicki L, Marquitz AR, et al. (2008) Nucleocytoplasmic trafficking of G2/M regulators in yeast. Molecular Biology of the Cell. 19: 4006-18
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