John M. Crutchley, Ph.D.

Affiliations: 
2008 Duke University, Durham, NC 
Area:
Genetics, Cell Biology
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"John Crutchley"

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Daniel Lew grad student 2008 Duke
 (Sensing cell shape: How does Sacharomyces cerevisiae regulate Hsl1p.)
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Publications

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Woods BL, Cannon KS, Vogt EJD, et al. (2021) Interplay of septin amphipathic helices in sensing membrane-curvature and filament bundling. Molecular Biology of the Cell. mbcE20050303
McLaughlin GA, Langdon EM, Crutchley JM, et al. (2020) Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking. Molecular Biology of the Cell. mbcE20030210
Smith JA, Curry EG, Blue RE, et al. (2020) FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells. The Journal of Cell Biology. 219
Cannon KS, Woods BL, Crutchley JM, et al. (2019) An amphipathic helix enables septins to sense micrometer-scale membrane curvature. The Journal of Cell Biology
Langdon EM, Qiu Y, Ghanbari Niaki A, et al. (2018) mRNA structure determines specificity of a polyQ-driven phase separation. Science (New York, N.Y.)
Chen J, Crutchley J, Zhang D, et al. (2017) Identification of a DNA Damage-induced Alternative Splicing Pathway that Regulates p53 and Cellular Senescence Markers. Cancer Discovery
Kastan MB, Scarbrough P, Chen J, et al. (2017) Abstract IA17: Non-canonical aspects of ATM and p53 signaling pathways Molecular Cancer Research. 15
Crutchley J, King KM, Keaton MA, et al. (2009) Molecular dissection of the checkpoint kinase Hsl1p. Molecular Biology of the Cell. 20: 1926-36
Szkotnicki L, Crutchley JM, Zyla TR, et al. (2008) The checkpoint kinase Hsl1p is activated by Elm1p-dependent phosphorylation. Molecular Biology of the Cell. 19: 4675-86
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