Diane Merry
Affiliations: | Biochemistry and Molecular Biology | Thomas Jefferson University, Philadelphia, PA, United States |
Area:
Molecular BiologyGoogle:
"Diane Merry"Children
Sign in to add trainee| Jill M. Yersak | grad student | 2011 | Thomas Jefferson |
| Erin M. Heine | grad student | 2013 | Thomas Jefferson |
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Publications
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| Richardson K, Sengupta M, Sujkowski A, et al. (2024) A phenotypically robust model of spinal and bulbar muscular atrophy in Drosophila. Journal of Neuroscience Research. 102: e25278 |
| Garcia Castro DR, Mazuk JR, Heine EM, et al. (2023) Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice. Iscience. 26: 107375 |
| Sengupta M, Pluciennik A, Merry DE. (2022) The role of ubiquitination in spinal and bulbar muscular atrophy. Frontiers in Molecular Neuroscience. 15: 1020143 |
| Molotsky E, Liu Y, Lieberman AP, et al. (2022) Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy. Acta Neuropathologica Communications. 10: 97 |
| Pluciennik A, Liu Y, Molotsky E, et al. (2020) Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy. The Journal of Clinical Investigation |
| Arnold FJ, Merry DE. (2019) Molecular Mechanisms and Therapeutics for SBMA/Kennedy's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics |
| Arnold FJ, Pluciennik A, Merry DE. (2019) Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy. Scientific Reports. 9: 119 |
| Yersak JM, Montie HL, Chevalier-Larsen ES, et al. (2017) The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms. Frontiers in Molecular Neuroscience. 10: 159 |
| Bott LC, Salomons FA, Maric D, et al. (2016) The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C(Cdh1) ubiquitin ligase complex. Scientific Reports. 6: 27703 |
| Zboray L, Pluciennik A, Curtis D, et al. (2015) Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA. Cell Reports |