John J. Turchi

1993-2005 Wright State University, Fairborn, OH, United States 
 2005- Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Biochemistry, Cell Biology
"John Joseph Turchi"


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Beryl John Ortwerth grad student 1990 University of Missouri - Columbia (Chemistry Tree)
 (Characterization of a temperature sensitive, cell cycle mutant from hamster cells.)
Robert A. Bambara post-doc 1990-1993 Rochester (Chemistry Tree)
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Turchi JJ, VanderVere-Carozza PS. (2019) Small-Molecule Inhibitor Screen for DNA Repair Proteins. Methods in Molecular Biology (Clifton, N.J.). 1999: 217-221
Pawelczak KS, Gavande NS, VanderVere-Carozza PS, et al. (2017) Modulating DNA Repair Pathways to Improve Precision Genome Engineering. Acs Chemical Biology
Gavande NS, VanderVere-Carozza P, Mishra AK, et al. (2017) Design and Structure-Guided Development of Novel Inhibitors of the Xeroderma Pigmentosum Group A (XPA) Protein-DNA Interaction. Journal of Medicinal Chemistry
Sears CR, Cooney SA, Chin-Sinex H, et al. (2016) DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer. Dna Repair. 40: 35-46
Gavande NS, VanderVere-Carozza PS, Hinshaw HD, et al. (2016) DNA repair targeted therapy: The past or future of cancer treatment? Pharmacology & Therapeutics
Woods DS, Sears CR, Turchi JJ. (2015) Recognition of DNA Termini by the C-Terminal Region of the Ku80 and the DNA-Dependent Protein Kinase Catalytic Subunit. Plos One. 10: e0127321
Mishra AK, Dormi SS, Turchi AM, et al. (2015) Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancer. Biochemical Pharmacology. 93: 25-33
Fang F, Munck J, Tang J, et al. (2014) The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 6504-16
Turchi JJ, Woods DS, VanderVere-Carozza P. (2014) Testing the metal of ERCC2 in predicting the response to platinum-based therapy. Cancer Discovery. 4: 1118-9
Peng X, Wang F, Li L, et al. (2014) Exploring a structural protein-drug interactome for new therapeutics in lung cancer. Molecular Biosystems. 10: 581-91
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