Thomas J. Cradick, Ph.D.
Affiliations: | 2009 | Molecular & Cell Biology | University of Iowa, Iowa City, IA |
Area:
General Biology, Molecular Biology, Cell BiologyGoogle:
"Thomas Cradick"Parents
Sign in to add mentor| Anton P. McCaffrey | grad student | 2009 | University of Iowa | |
| (Designing zinc finger nucleases that specifically cleave hepatitis B viral DNA.) | ||||
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Publications
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| Burdo TH, Chen C, Kaminski R, et al. (2023) Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates. Gene Therapy |
| Schneller JL, Lee CM, Venturoni LE, et al. (2021) genome editing at the albumin locus to treat methylmalonic acidemia. Molecular Therapy. Methods & Clinical Development. 23: 619-632 |
| Antoniani C, Meneghini V, Lattanzi A, et al. (2018) Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus. Blood |
| Zhao J, Akinsanmi I, Arafat D, et al. (2016) A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood. American Journal of Human Genetics. 98: 299-309 |
| Lee CM, Cradick TJ, Bao G. (2016) The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Lee CM, Cradick TJ, Fine EJ, et al. (2016) Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Suzuki S, Sargent RG, Illek B, et al. (2016) TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs. Molecular Therapy. Nucleic Acids. 5: e273 |
| Lin MI, Paik EJ, Mishra BP, et al. (2016) Re-Creating Hereditary Persistence of Fetal Hemoglobin (HPFH) to Treat Sickle Cell Disease (SCD) and β-Thalassemia Blood. 128: 4708-4708 |
| Mishra B, Chou S, Lin MI, et al. (2016) Crispr/Cas9- Mediated Genome Editing of Human CD34+ Cells Upregulate Fetal Hemoglobin to Clinically Relevant Levels in Single Cell-Derived Erythroid Colonies Blood. 128: 3623-3623 |
| Antoniani C, Meneghini V, Lattanzi A, et al. (2016) Induction of Fetal Hemoglobin Synthesis By Crispr/Cas9-Mediated Disruption of the β-Globin Locus Architecture Blood. 128: 321-321 |