Jesse E. Otero, Ph.D.

Affiliations: 
2011 Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology, Cell Biology
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"Jesse Otero"

Parents

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Yousef Abu-Amer grad student 2011 Washington University
 (The role of IKKbeta in osteoclastogenesis and inflammatory osteolysis.)
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Publications

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Arra M, Swarnkar G, Ke K, et al. (2020) LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis. Nature Communications. 11: 3427
Otero JE, Martin JR, Rowe TM, et al. (2019) Radiographic and Clinical Outcomes of Modular Tapered Fluted Stems for Femoral Revision for Paprosky III and IV Femoral Defects or Vancouver B2 and B3 Femoral Fractures. The Journal of Arthroplasty
Otero JE, Stevens JW, Malandra AE, et al. (2014) Osteoclast inhibition impairs chondrosarcoma growth and bone destruction. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 1562-71
Cassel SL, Janczy JR, Bing X, et al. (2014) Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 1072-7
Zhang Y, Otero JE, Abu-Amer Y. (2013) Ubiquitin-like domain of IKKβ regulates osteoclastogenesis and osteolysis. Calcified Tissue International. 93: 78-85
Otero JE, Gottesman GS, McAlister WH, et al. (2013) Severe skeletal toxicity from protracted etidronate therapy for generalized arterial calcification of infancy. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 419-30
Otero JE, Chen T, Zhang K, et al. (2012) Constitutively active canonical NF-κB pathway induces severe bone loss in mice. Plos One. 7: e38694
Darwech I, Otero JE, Alhawagri MA, et al. (2010) Tyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation and function in osteoclastogenesis. The Journal of Biological Chemistry. 285: 25522-30
Otero JE, Dai S, Alhawagri MA, et al. (2010) IKKbeta activation is sufficient for RANK-independent osteoclast differentiation and osteolysis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1282-94
Darwech I, Otero J, Alhawagri M, et al. (2009) Impediment of NEMO oligomerization inhibits osteoclastogenesis and osteolysis. Journal of Cellular Biochemistry. 108: 1337-45
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