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Yiyuan Yin, Ph.D.

Affiliations: 
2010 Molecular and Cell Biology University of Maryland, College Park, College Park, MD 
Area:
Molecular Biology, Biochemistry, General Biophysics
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"Yiyuan Yin"
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Roy A. Mariuzza grad student 2010 University of Maryland
 (Structural basis for escaping negative selection by T cell receptor with high affinity for self antigen.)

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Publications

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Zhang Y, Yin Y, Zhang S, et al. (2016) HIV-1 Infection-Induced Suppression of the Let-7i/IL-2 Axis Contributes to CD4(+) T Cell Death. Scientific Reports. 6: 25341
Fontanili L, Lancilli C, Suzui N, et al. (2016) Kinetic Analysis of Zinc/Cadmium Reciprocal Competitions Suggests a Possible Zn-Insensitive Pathway for Root-to-Shoot Cadmium Translocation in Rice. Rice (New York, N.Y.). 9: 16
He Y, Rangarajan S, Kerzic M, et al. (2015) Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR. The Journal of Biological Chemistry
Li Y, Yin Y, Mariuzza RA. (2013) Structural and biophysical insights into the role of CD4 and CD8 in T cell activation. Frontiers in Immunology. 4: 206
Yin Y, Li Y, Mariuzza RA. (2012) Structural basis for self-recognition by autoimmune T-cell receptors. Immunological Reviews. 250: 32-48
Yin Y, Wang XX, Mariuzza RA. (2012) Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proceedings of the National Academy of Sciences of the United States of America. 109: 5405-10
Wang XX, Li Y, Yin Y, et al. (2011) Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proceedings of the National Academy of Sciences of the United States of America. 108: 15960-5
Yin Y, Li Y, Kerzic MC, et al. (2011) Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection. The Embo Journal. 30: 1137-48
Yin Y, Mariuzza RA. (2009) The multiple mechanisms of T cell receptor cross-reactivity. Immunity. 31: 849-51
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