Asad Taherbhoy, Ph.D.

Affiliations: 
2011 Cell Biology and Biochemistry University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Biochemistry
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"Asad Taherbhoy"

Parents

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Brenda A. Schulman grad student 2011 UTHSC
 (Novel insights into ubiquitin-like protein E1-E2 interactions.)
Andrea G. Cochran post-doc Genentech, Inc. (Chemistry Tree)
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Publications

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Taherbhoy AM, Daniels DL. (2023) Harnessing UBR5 for targeted protein degradation of key transcriptional regulators. Trends in Pharmacological Sciences. 44: 758-761
Qiu Y, Zheng Y, Taherbhoy AM, et al. (2017) Crystallographic Characterization of ATG Proteins and Their Interacting Partners. Methods in Enzymology. 587: 227-246
Taherbhoy AM, Huang OW, Cochran AG. (2015) BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase. Nature Communications. 6: 7621
Kaiser SE, Mao K, Taherbhoy AM, et al. (2012) Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures. Nature Structural & Molecular Biology. 19: 1242-9
Taherbhoy AM, Schulman BA, Kaiser SE. (2012) Ubiquitin-like modifiers. Essays in Biochemistry. 52: 51-63
Taherbhoy AM, Kaiser SE, Schulman BA. (2012) Trans mechanism for ubiquitin-like protein transfer in autophagy. Cell Cycle (Georgetown, Tex.). 11: 635-6
Taherbhoy AM, Tait SW, Kaiser SE, et al. (2011) Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway. Molecular Cell. 44: 451-61
Wang J, Taherbhoy AM, Hunt HW, et al. (2010) Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways. Plos One. 5: e15805
Huang DT, Ayrault O, Hunt HW, et al. (2009) E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. Molecular Cell. 33: 483-95
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