Irit Zurer, Ph.D.

Affiliations: 
2003 Weizmann Institute of Science, Rehovot, Israel 
Area:
Molecular Biology
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"Irit Zurer"

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Varda Rotter grad student 2003 Weizmann Institute
 (The role of p53 in the DNA repair machinery.)
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Publications

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Zurer I, Hofseth LJ, Cohen Y, et al. (2004) The role of p53 in base excision repair following genotoxic stress. Carcinogenesis. 25: 11-9
Hofseth LJ, Khan MA, Ambrose M, et al. (2003) The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. The Journal of Clinical Investigation. 112: 1887-94
Hofseth LJ, Saito S, Hussain SP, et al. (2003) Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proceedings of the National Academy of Sciences of the United States of America. 100: 143-8
Offer H, Erez N, Zurer I, et al. (2002) The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA. Carcinogenesis. 23: 1025-32
Milyavsky M, Mimran A, Senderovich S, et al. (2001) Activation of p53 protein by telomeric (TTAGGG)n repeats. Nucleic Acids Research. 29: 5207-15
Offer H, Milyavsky M, Erez N, et al. (2001) Structural and functional involvement of p53 in BER in vitro and in vivo. Oncogene. 20: 581-9
Seluanov A, Gorbunova V, Falcovitz A, et al. (2001) Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53. Molecular and Cellular Biology. 21: 1552-64
Offer H, Zurer I, Banfalvi G, et al. (2001) p53 modulates base excision repair activity in a cell cycle-specific manner after genotoxic stress. Cancer Research. 61: 88-96
Zhou X, Wang XW, Xu L, et al. (1999) COOH-terminal domain of p53 modulates p53-mediated transcriptional transactivation, cell growth, and apoptosis. Cancer Research. 59: 843-8
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