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Alicia M. McCarthy, Ph.D.

Affiliations: 
2007 Cellular and Integrative Physiology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Physiology Biology
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"Alicia McCarthy"
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Jeffrey S. Elmendorf grad student 2007 Indiana University
 (Membrane and cytoskeletal mechanisms of insulin-induced insulin resistance in skeletal muscle.)

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Publications

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Bhonagiri P, Pattar GR, Habegger KM, et al. (2011) Evidence coupling increased hexosamine biosynthesis pathway activity to membrane cholesterol toxicity and cortical filamentous actin derangement contributing to cellular insulin resistance. Endocrinology. 152: 3373-84
Horvath EM, Tackett L, McCarthy AM, et al. (2010) Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance (Molecular Endocrinology (2008) 22, (937-950) DOI: 10.1210/me.2007-0410) Molecular Endocrinology. 24: 1308
Bhonagiri P, Pattar GR, Horvath EM, et al. (2010) Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin (Endocrinology (2009) 150, (1636-1645) DOI: 10.1210/en.2008-1102) Endocrinology. 151: 2967
Bhonagiri P, Pattar GR, Horvath EM, et al. (2009) Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin. Endocrinology. 150: 1636-45
Horvath EM, Tackett L, McCarthy AM, et al. (2008) Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance. Molecular Endocrinology (Baltimore, Md.). 22: 937-50
McCarthy AM, Elmendorf JS. (2007) GLUT4's itinerary in health & disease. The Indian Journal of Medical Research. 125: 373-88
McCarthy AM, Spisak KO, Brozinick JT, et al. (2006) Loss of cortical actin filaments in insulin-resistant skeletal muscle cells impairs GLUT4 vesicle trafficking and glucose transport. American Journal of Physiology. Cell Physiology. 291: C860-8
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