Patricia J. Keller, Ph.D.

Affiliations: 
2005 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology, Cell Biology
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"Patricia Keller"

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Adrienne D. Cox grad student 2005 UNC Chapel Hill
 (Characterization of the small GTPase Rac3 in signaling and transformation.)
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Publications

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Conery AR, Park S, Steinbaugh MJ, et al. (2019) Abstract 4351: Single-cell RNA sequencing reveals transcriptomic heterogeneity in response to epigenetic inhibitors Cancer Research. 79: 4351-4351
Keller PJ, Conery AR, Centore RC, et al. (2016) Abstract 4749: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma Cancer Research. 76: 4749-4749
Madigan JP, Bodemann BO, Brady DC, et al. (2009) Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation. The Biochemical Journal. 424: 153-61
Roberts PJ, Mitin N, Keller PJ, et al. (2008) Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification. The Journal of Biological Chemistry. 283: 25150-63
Thomas EK, Cancelas JA, Chae HD, et al. (2007) Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease. Cancer Cell. 12: 467-78
Thomas EK, Cancelas JA, Chae H, et al. (2007) Rac GTPases Are Potential Therapeutic Targets in p210-BCR-ABL-Induced Myeloproliferative Disease (MPD). Blood. 110: 465-465
Fiordalisi JJ, Keller PJ, Cox AD. (2006) PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility. Cancer Research. 66: 3153-61
Keller PJ, Fiordalisi JJ, Berzat AC, et al. (2005) Visual monitoring of post-translational lipid modifications using EGFP-GTPase probes in live cells. Methods (San Diego, Calif.). 37: 131-37
Keller PJ, Gable CM, Wing MR, et al. (2005) Rac3-mediated transformation requires multiple effector pathways. Cancer Research. 65: 9883-90
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