Donita C. Brady, Ph.D.
Affiliations: | 2008 | Pharmacology | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Cell Biology, Molecular BiologyGoogle:
"Donita Brady"Parents
Sign in to add mentor| Adrienne D. Cox | grad student | 2008 | UNC Chapel Hill | |
| (The transforming Rho family GTPase, Wrch -1, regulates epithelial cell morphogenesis through modulating cell junctions and actin cytoskeletal dynamics.) | ||||
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Publications
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| Chojnowski JE, Li R, Tsang T, et al. (2022) Copper Modulates the Catalytic Activity of Protein Kinase CK2. Frontiers in Molecular Biosciences. 9: 878652 |
| Brady DC, Hmeljak J, Dar AC. (2022) Understanding and drugging RAS: 40 years to break the tip of the iceberg. Disease Models & Mechanisms. 15 |
| Tsang T, Posimo JM, Gudiel AA, et al. (2020) Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma. Nature Cell Biology |
| Kim YJ, Tsang T, Anderson GR, et al. (2020) Inhibition of BCL2 family members increases the efficacy of copper chelation in BRAFV600E-driven melanoma. Cancer Research |
| Rasool RU, Natesan R, Deng Q, et al. (2019) CDK7 inhibition suppresses Castration-Resistant Prostate Cancer through MED1 inactivation. Cancer Discovery |
| Chung CY, Posimo JM, Lee S, et al. (2019) Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism. Proceedings of the National Academy of Sciences of the United States of America |
| Kim YJ, Bond GJ, Tsang T, et al. (2019) Copper chaperone ATOX1 is required for MAPK signaling and growth in BRAF mutation-positive melanoma. Metallomics : Integrated Biometal Science |
| Katona BW, Glynn RA, Paulosky KE, et al. (2019) Combined menin and EGFR inhibitors synergize to suppress colorectal cancer via EGFR-independent and calcium-mediated repression of SKP2 transcription. Cancer Research |
| Rasool R, Natesan R, deng q, et al. (2019) Abstract B016: CDK7 inhibition suppresses AR addicted Castration-Resistant Prostate Cancer through MED1 inactivation Molecular Cancer Therapeutics. 18 |
| Sadeghi RS, Kulej K, Kathayat RS, et al. (2018) Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior. Elife. 7 |