Cynthia M. Holsclaw, Ph.D.

Affiliations: 
2010 Biochemistry and Molecular Biology University of California, Davis, Davis, CA 
Area:
Biochemistry, Molecular Biology, Parasitology Biology
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"Cynthia Holsclaw"

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Julie A. Leary grad student 2010 UC Davis
 (Characterization of Virulence Metabolites Produced by Mycobacterium tuberculosis: A Mass Spectrometric Approach.)
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Publications

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Sogi KM, Holsclaw CM, Fragiadakis GK, et al. (2016) Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis. Acs Infectious Diseases. 2: 800-806
Miller RL, Dykstra AB, Wei W, et al. (2016) Enrichment of two isomeric heparin oligosaccharides exhibiting different affinities towards MCP-1. Analytical Chemistry
Touchette MH, Holsclaw CM, Previti ML, et al. (2015) The rv1184c locus encodes Chp2, an acyltransferase in Mycobacterium tuberculosis polyacyltrehalose lipid biosynthesis. Journal of Bacteriology. 197: 201-10
Swarts BM, Holsclaw CM, Jewett JC, et al. (2012) Probing the mycobacterial trehalome with bioorthogonal chemistry. Journal of the American Chemical Society. 134: 16123-6
Marquez BV, Beck HE, Aweda TA, et al. (2012) Enhancing peptide ligand binding to vascular endothelial growth factor by covalent bond formation. Bioconjugate Chemistry. 23: 1080-9
Gilmore SA, Schelle MW, Holsclaw CM, et al. (2012) Sulfolipid-1 biosynthesis restricts Mycobacterium tuberculosis growth in human macrophages. Acs Chemical Biology. 7: 863-70
Seeliger JC, Holsclaw CM, Schelle MW, et al. (2012) Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 287: 7990-8000
Holsclaw CM, Muse WB, Carroll KS, et al. (2011) Mass Spectrometric Analysis of Mycothiol levels in Wild-Type and Mycothiol Disulfide Reductase Mutant Mycobacterium smegmatis. International Journal of Mass Spectrometry. 305: 151-156
Hatzios SK, Schelle MW, Newton GL, et al. (2011) The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth. Bioorganic & Medicinal Chemistry Letters. 21: 4956-9
Hatzios SK, Schelle MW, Holsclaw CM, et al. (2009) PapA3 is an acyltransferase required for polyacyltrehalose biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 284: 12745-51
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