Chad R. Deisenroth, Ph.D.

Affiliations: 
2010 Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics
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"Chad Deisenroth"

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Yanping Zhang grad student 2010 UNC Chapel Hill
 (Regulation and function of mitochondrial Hep27: A novel modulator of the Mdm2-p53 pathway.)
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Publications

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Di J, Tang J, Qian H, et al. (2017) p53 upregulates PLCε-IP3-Ca(2+) pathway and inhibits autophagy through its target gene Rap2B. Oncotarget. 8: 64657-64669
Liu Y, Deisenroth C, Zhang Y. (2016) RP-MDM2-p53 Pathway: Linking Ribosomal Biogenesis and Tumor Surveillance. Trends in Cancer. 2: 191-204
Deisenroth C, Franklin DA, Zhang Y. (2016) The Evolution of the Ribosomal Protein-MDM2-p53 Pathway. Cold Spring Harbor Perspectives in Medicine. 6
Deisenroth C, Zhang Y. (2011) The Ribosomal Protein-Mdm2-p53 Pathway and Energy Metabolism: Bridging the Gap between Feast and Famine. Genes & Cancer. 2: 392-403
Deisenroth C, Itahana Y, Tollini L, et al. (2011) p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation. The Journal of Biological Chemistry. 286: 28343-56
Macias E, Jin A, Deisenroth C, et al. (2010) An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction. Cancer Cell. 18: 231-43
Deisenroth C, Thorner AR, Enomoto T, et al. (2010) Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53. Molecular and Cellular Biology. 30: 3981-93
Lindström MS, Deisenroth C, Zhang Y. (2007) Putting a Finger on Growth Surveillance Insight into MDM2 Zinc Finger-Ribosomal Protein Interactions Cell Cycle. 6: 434-437
Lindström MS, Jin A, Deisenroth C, et al. (2007) Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation. Molecular and Cellular Biology. 27: 1056-68
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