Ruojing Yang, Ph.D.

Affiliations: 
2000 Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Cell Biology
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"Ruojing Yang"

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Ronald C. Wek grad student 2000 Indiana University
 (Regulation of glycogen metabolism and translational control in response to nutritional limitation.)
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Publications

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Yang R, Lacson RG, Castriota G, et al. (2012) A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis. Plos One. 7: e36384
Zhang XD, Santini F, Lacson R, et al. (2011) cSSMD: assessing collective activity for addressing off-target effects in genome-scale RNA interference screens. Bioinformatics (Oxford, England). 27: 2775-81
Yang R, Wilcox DM, Haasch DL, et al. (2007) Liver-specific knockdown of JNK1 up-regulates proliferator-activated receptor gamma coactivator 1 beta and increases plasma triglyceride despite reduced glucose and insulin levels in diet-induced obese mice. The Journal of Biological Chemistry. 282: 22765-74
Liu G, Lynch JK, Freeman J, et al. (2007) Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors. Journal of Medicinal Chemistry. 50: 3086-100
Lin J, Yang R, Tarr PT, et al. (2005) Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. Cell. 120: 261-73
Yoon JC, Xu G, Deeney JT, et al. (2003) Suppression of beta cell energy metabolism and insulin release by PGC-1alpha. Developmental Cell. 5: 73-83
Lin J, Tarr PT, Yang R, et al. (2003) PGC-1beta in the regulation of hepatic glucose and energy metabolism. The Journal of Biological Chemistry. 278: 30843-8
St-Pierre J, Lin J, Krauss S, et al. (2003) Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. The Journal of Biological Chemistry. 278: 26597-603
Gasa R, Clark C, Yang R, et al. (2002) Reversal of diet-induced glucose intolerance by hepatic expression of a variant glycogen-targeting subunit of protein phosphatase-1. The Journal of Biological Chemistry. 277: 1524-30
Yang R, Wek SA, Wek RC. (2000) Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase. Molecular and Cellular Biology. 20: 2706-17
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