Kirk A. Staschke, Ph.D.
Affiliations: | 2010 | Biochemistry and Molecular Biology | Indiana University, Bloomington, Bloomington, IN, United States |
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Molecular BiologyGoogle:
"Kirk Staschke"Parents
Sign in to add mentorRonald C. Wek | grad student | 2010 | Indiana University | |
(Integration of general amino acid control and Tor regulatory pathways in yeast.) |
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Publications
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Levy JL, Mirek ET, Rodriguez EM, et al. (2023) GCN2 is required to maintain core body temperature in mice during acute cold. American Journal of Physiology. Endocrinology and Metabolism |
Stokes ME, Calvo V, Fujisawa S, et al. (2023) PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
Mijit M, Boner M, Cordova RA, et al. (2023) Activation of the integrated stress response (ISR) pathways in response to Ref-1 inhibition in human pancreatic cancer and its tumor microenvironment. Frontiers in Medicine. 10: 1146115 |
Wek RC, Anthony TG, Staschke KA. (2023) Surviving and adapting to stress: Translational control and the integrated stress response. Antioxidants & Redox Signaling |
Carlson KR, Georgiadis MM, Tameire F, et al. (2023) Activation of Gcn2 by small molecules designed to be inhibitors. The Journal of Biological Chemistry. 299: 104595 |
Srivastava S, Jiang J, Misra J, et al. (2022) Asparagine bioavailability regulates the translation of MYC oncogene. Oncogene |
Cordova RA, Misra J, Amin PH, et al. (2022) GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis. Elife. 11 |
Staschke KA, Wek RC. (2019) Adapting to cell stress from inside and out. Nature Cell Biology. 21: 799-800 |
Augusto L, Martynowicz J, Staschke KA, et al. (2018) Effects of PERK eIF2α kinase inhibitor against . Antimicrobial Agents and Chemotherapy |
Krishnamoorthy J, Tenkerian C, Gupta J, et al. (2018) Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells. Cell Death & Disease. 9: 254 |