Lizbeth Hedstrom

Affiliations: 
Molecular and Cell Biology Brandeis University, Waltham, MA, United States 
Area:
Molecular Biology, Pathology
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"Lizbeth Hedstrom"

Parents

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Robert Heinz Abeles grad student Brandeis (Chemistry Tree)
C. C. Wang post-doc UCSF (Chemistry Tree)

Children

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Jennifer A. Digits grad student 2000 Brandeis
Jeremy E. McLean grad student 2003 Brandeis
Christopher T. Knoell grad student 2004 Brandeis
Yollete V. Guillen Schlippe grad student 2005 Brandeis
Sarah E. Mortimer grad student 2005 Brandeis
Thomas V. Riera grad student 2007 Brandeis
Brian C. Hoefler grad student 2010 Brandeis
Dharia A. McGrew grad student 2012 Brandeis
Dong Xu post-doc 2006-2008 Brandeis (Chemistry Tree)
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Publications

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Kaushansky A, Hedstrom L, Goldman A, et al. (2018) A call to arms: Unifying the fight against resistance. Science Signaling. 11
Wei Y, Kuzmic P, Yu R, et al. (2016) Inhibition of IMPDH from Bacillus anthracis: Mechanism revealed by pre-steady state kinetics. Biochemistry
Makowska-Grzyska M, Kim Y, Maltseva N, et al. (2015) A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity. The Journal of Biological Chemistry. 290: 5893-911
Makowska-Grzyska M, Kim Y, Wu R, et al. (2012) Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes. Biochemistry. 51: 6148-63
McGrew DA, Hedstrom L. (2012) Towards a pathological mechanism for IMPDH1-linked retinitis pigmentosa. Advances in Experimental Medicine and Biology. 723: 539-45
Riera TV, Zheng L, Josephine HR, et al. (2011) Allosteric activation via kinetic control: potassium accelerates a conformational change in IMP dehydrogenase. Biochemistry. 50: 8508-18
Hoefler BC, Gollapalli DR, Hedstrom L. (2011) Specific biotinylation of IMP dehydrogenase. Bioorganic & Medicinal Chemistry Letters. 21: 1363-5
Mansfield BE, Oltean HN, Oliver BG, et al. (2010) Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi. Plos Pathogens. 6: e1001126
Spellicy CJ, Xu D, Cobb G, et al. (2010) Investigating the mechanism of disease in the RP10 form of retinitis pigmentosa. Advances in Experimental Medicine and Biology. 664: 541-8
Sun XE, Sharling L, Muthalagi M, et al. (2010) Prodrug activation by Cryptosporidium thymidine kinase. The Journal of Biological Chemistry. 285: 15916-22
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