Hongwu Chen

Affiliations: 
Biochemistry and Molecular Biology University of California, Davis, Davis, CA 
Area:
Molecular Biology, Oncology
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"Hongwu Chen"
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Publications

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Kong X, Yan W, Sun W, et al. (2023) Isoform-specific disruption of the gene reveals a critical role for TAp73γ in tumorigenesis via leptin. Elife. 12
Zou H, Yang Y, Chen HW. (2023) Natural compounds ursolic acid and digoxin exhibit inhibitory activities to cancer cells in RORγ-dependent and -independent manner. Frontiers in Pharmacology. 14: 1146741
Ning S, Zhao J, Lombard AP, et al. (2022) Activation of neural lineage networks and ARHGEF2 in enzalutamide-resistant and neuroendocrine prostate cancer and association with patient outcomes. Communications Medicine. 2: 118
Yang N, Yang Y, Huang Z, et al. (2022) Deregulation of Cholesterol Homeostasis by a Nuclear Hormone Receptor Crosstalk in Advanced Prostate Cancer. Cancers. 14
Zou H, Yang Y, Shi Z, et al. (2022) Nuclear receptor RORγ inverse agonists/antagonists display tissue- and gene-context selectivity through distinct activities in altering chromatin accessibility and master regulator SREBP2 occupancy. Pharmacological Research. 182: 106324
Wang H, Wang Q, Cai G, et al. (2021) Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop NRF2 in cancer therapeutic resistance. Acta Pharmaceutica Sinica. B. 12: 1871-1884
Hsu SC, Chen CL, Cheng ML, et al. (2021) Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes. Theranostics. 11: 7527-7545
Zhang X, Huang Z, Wang J, et al. (2021) Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling. Cancers. 13
Zheng J, Wang J, Wang Q, et al. (2020) Targeting castration-resistant prostate cancer with a novel ROR antagonist elaiophylin. Acta Pharmaceutica Sinica. B. 10: 2313-2322
Candas-Green D, Xie B, Huang J, et al. (2020) Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nature Communications. 11: 4591
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