Sarah E. Mortimer, Ph.D.

2005 Brandeis University, Waltham, MA, United States 
Molecular Biology
"Sarah Mortimer"


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Lizbeth Hedstrom grad student 2005 Brandeis
 (Non-enzymatic functions of human inosine 5'-monophosphate dehydrogenase: Disruption of nucleic acid binding by retinal disease mutations and a connection to translation.)
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Mortimer SE, Xu D, McGrew D, et al. (2008) IMP dehydrogenase type 1 associates with polyribosomes translating rhodopsin mRNA. The Journal of Biological Chemistry. 283: 36354-60
Bowne SJ, Sullivan LS, Mortimer SE, et al. (2006) Spectrum and frequency of mutations in IMPDH1 associated with autosomal dominant retinitis pigmentosa and leber congenital amaurosis. Investigative Ophthalmology & Visual Science. 47: 34-42
Mortimer SE, Hedstrom L. (2005) Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding. The Biochemical Journal. 390: 41-7
McLean JE, Hamaguchi N, Belenky P, et al. (2004) Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo. The Biochemical Journal. 379: 243-51
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