Michael A. Kalwat, Ph.D.

Affiliations: 
2007-2012 Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
 2012-2020 Pharmacology University of Texas Southwester Medical Center, Dallas, TX, United States 
 2020- Lilly Diabetes Center of Excellence Indiana Biosciences Research Institute 
Area:
Diabetes, Islet Biology, regulation of hormone secretion
Website:
www.linkedin.com/in/michael-kalwat
Google:
"Michael Kalwat"

Parents

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James D. Forney research assistant Purdue (Chemistry Tree)
Debbie C. Thurmond grad student 2012 Indiana University
 (F-actin regulation of snare-mediated insulin secretion.)
Melanie Cobb post-doc 2012- University of Texas Southwester Medical Center (FlyTree)
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Publications

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Roy G, Syed R, Lazaro O, et al. (2024) Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning. Biorxiv : the Preprint Server For Biology
Mukherjee N, Contreras CJ, Lin L, et al. (2024) RIPK3 promotes islet amyloid-induced β-cell loss and glucose intolerance in a humanized mouse model of type 2 diabetes. Molecular Metabolism. 101877
Kalwat MA, Rodrigues-Dos-Santos K, Binns DD, et al. (2023) Small molecule glucagon release inhibitors with activity in human islets. Frontiers in Endocrinology. 14: 1114799
Goode RA, Hum JM, Kalwat MA. (2022) Therapeutic Strategies Targeting Pancreatic Islet β-Cell Proliferation, Regeneration, and Replacement. Endocrinology. 164
Rodrigues-Dos-Santos K, Roy G, Binns DD, et al. (2022) Small molecule-mediated insulin hypersecretion induces transient ER stress response and loss of beta cell function. Endocrinology
Kalwat MA, Scheuner D, Rodrigues Dos Santos K, et al. (2021) The pancreatic β cell response to secretory demands and adaption to stress. Endocrinology
Kalwat MA. (2021) Correction to: High-Throughput Screening for Insulin Secretion Modulators. Methods in Molecular Biology (Clifton, N.J.). 2233: C1
Kalwat MA. (2021) High-Throughput Screening for Insulin Secretion Modulators. Methods in Molecular Biology (Clifton, N.J.). 2233: 131-138
Kalwat MA, Huang Z, Binns DD, et al. (2020) α-Adrenergic Disruption of β Cell BDNF-TrkB Receptor Tyrosine Kinase Signaling. Frontiers in Cell and Developmental Biology. 8: 576396
Kalwat M, Cobb MH. (2019) Measuring Relative Insulin Secretion using a Co-Secreted Luciferase Surrogate. Journal of Visualized Experiments : Jove
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