Philip Coffino

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
proteasomes
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"Philip Coffino"
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Coffino P, Too PH, Erales J. (2014) Slippery substrates impair ATP-dependent protease function by slowing unfolding. The Journal of Biological Chemistry. 289: 3826
Erales J, Coffino P. (2014) Ubiquitin-independent proteasomal degradation. Biochimica Et Biophysica Acta. 1843: 216-21
Park S, Li X, Kim HM, et al. (2013) Reconfiguration of the proteasome during chaperone-mediated assembly. Nature. 497: 512-6
Too PH, Erales J, Simen JD, et al. (2013) Slippery substrates impair function of a bacterial protease ATPase by unbalancing translocation versus exit. The Journal of Biological Chemistry. 288: 13243-57
Karpov D, Glickman MH, Bar-Nun S, et al. (2012) Ubiquitin proteasome system in stress and disease. Biochemistry Research International. 2012: 454796
Erales J, Hoyt MA, Troll F, et al. (2012) Functional asymmetries of proteasome translocase pore. The Journal of Biological Chemistry. 287: 18535-43
Henderson A, Erales J, Hoyt MA, et al. (2011) Dependence of proteasome processing rate on substrate unfolding. The Journal of Biological Chemistry. 286: 17495-502
Hoyt MA, McDonough S, Pimpl SA, et al. (2008) A genetic screen for Saccharomyces cerevisiae mutants affecting proteasome function, using a ubiquitin-independent substrate. Yeast (Chichester, England). 25: 199-217
Takeuchi J, Chen H, Hoyt MA, et al. (2008) Structural elements of the ubiquitin-independent proteasome degron of ornithine decarboxylase. The Biochemical Journal. 410: 401-7
Takeuchi J, Chen H, Coffino P. (2007) Proteasome substrate degradation requires association plus extended peptide. The Embo Journal. 26: 123-31
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