Karishma Rajani, Ph.D.

Affiliations: 
2011 Biochemistry and Molecular Biology Wake Forest University, Winston-Salem, NC, United States 
Area:
Biochemistry, Virology Biology, Molecular Biology
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"Karishma Rajani"

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Douglas S. Lyles grad student 2011 Wake Forest
 (Matrix protein of vesicular stomatitis virus interacts with host Rae1 in multiple complexes to inhibit host transcription.)
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Publications

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Rajani KR, Vile RG. (2015) Harnessing the Power of Onco-Immunotherapy with Checkpoint Inhibitors. Viruses. 7: 5889-901
Blanchard M, Shim KG, Grams MP, et al. (2015) Definitive Management of Oligometastatic Melanoma in a Murine Model Using Combined Ablative Radiation Therapy and Viral Immunotherapy. International Journal of Radiation Oncology, Biology, Physics. 93: 577-87
Cockle JV, Rajani K, Zaidi S, et al. (2015) Combination viroimmunotherapy with checkpoint inhibition to treat glioma, based on location-specific tumor profiling. Neuro-Oncology
Rajani K, Parrish C, Kottke T, et al. (2015) Combination therapy with reovirus and anti-PD-1 blockade controls tumor growth through innate and adaptive immune responses. Molecular Therapy : the Journal of the American Society of Gene Therapy
Westcott MM, Liu J, Rajani K, et al. (2015) Interferon Beta and Interferon Alpha 2a Differentially Protect Head and Neck Cancer Cells from Vesicular Stomatitis Virus-Induced Oncolysis. Journal of Virology. 89: 7944-54
Zaidi S, Blanchard M, Shim K, et al. (2015) Mutated BRAF Emerges as a Major Effector of Recurrence in a Murine Melanoma Model After Treatment With Immunomodulatory Agents. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 845-56
Westcott MM, Liu J, Rajani K, et al. (2015) Interferon beta and interferon alpha 2a differentially protect head and neck cancer cells from vesicular stomatitis virus-induced oncolysis Journal of Virology. 89: 7944-7954
Alonso-Camino V, Rajani K, Kottke T, et al. (2014) The profile of tumor antigens which can be targeted by immunotherapy depends upon the tumor's anatomical site. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1936-48
Westcott MM, Ahmed M, Smedberg JR, et al. (2013) Preservation of dendritic cell function during vesicular stomatitis virus infection reflects both intrinsic and acquired mechanisms of resistance to suppression of host gene expression by viral M protein Journal of Virology. 87: 11730-11740
Rajani KR, Pettit Kneller EL, McKenzie MO, et al. (2012) Complexes of Vesicular Stomatitis Virus Matrix Protein with Host Rae1 and Nup98 Involved in Inhibition of Host Transcription Plos Pathogens. 8
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