Joshua W. Knowles, Ph.D.

Affiliations: 
2001 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics, Molecular Biology, Animal Physiology Biology
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"Joshua Knowles"

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Nobuyo Maeda grad student 2001 UNC Chapel Hill
 (Genetic modifiers of hypertension, atherosclerosis and cardiac hypertrophy in mice.)
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Publications

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Fathzadeh M, Li J, Rao A, et al. (2020) FAM13A affects body fat distribution and adipocyte function. Nature Communications. 11: 1465
Cook NL, Pjanic M, Emmerich AG, et al. (2019) CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation. Bmc Endocrine Disorders. 19: 115
Rao AS, Knowles JW. (2019) Polygenic risk scores in coronary artery disease. Current Opinion in Cardiology
Sarraju A, Knowles JW. (2019) Genetic Testing and Risk Scores: Impact on Familial Hypercholesterolemia. Frontiers in Cardiovascular Medicine. 6: 5
Sturm AC, Knowles JW, Gidding SS, et al. (2018) Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel. Journal of the American College of Cardiology. 72: 662-680
Rodriguez F, Knowles JW, Maron DJ, et al. (2018) Frequency of Statin Use in Patients With Low-Density Lipoprotein Cholesterol ≥190 mg/dl from the Veterans Affairs Health System. The American Journal of Cardiology
Knowles JW, Ashley EA. (2018) Cardiovascular disease: The rise of the genetic risk score. Plos Medicine. 15: e1002546
Helle EIT, Biegley P, Knowles JW, et al. (2017) First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring. The Journal of Pediatrics
Knowles JW, Zarafshar S, Pavlovic A, et al. (2017) Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study. Frontiers in Cardiovascular Medicine. 4: 53
Reaven GM, Knowles JW, Leonard D, et al. (2017) Relationship between simple markers of insulin resistance and coronary artery calcification. Journal of Clinical Lipidology
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