Timothy J. Ley

Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Molecular Biology, Cell Biology, Genetics
"Timothy Ley"
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Christopher MJ, Petti AA, Rettig MP, et al. (2018) Immune Escape of Relapsed AML Cells after Allogeneic Transplantation. The New England Journal of Medicine
Duncavage EJ, Jacoby MA, Chang GS, et al. (2018) Mutation Clearance after Transplantation for Myelodysplastic Syndrome. The New England Journal of Medicine. 379: 1028-1041
Trissal MC, Wong TN, Yao JC, et al. (2018) MIR142 loss-of-function mutations derepress ASH1L to increase HOXA gene expression and promote leukemogenesis. Cancer Research
Jacoby MA, Duncavage EJ, Chang GS, et al. (2018) Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant. Jci Insight. 3
Wong TN, Miller CA, Jotte MRM, et al. (2018) Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential. Nature Communications. 9: 455
Spencer DH, Russler-Germain DA, Ketkar S, et al. (2017) CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression. Cell
Duncavage EJ, Uy GL, Petti AA, et al. (2017) Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy. Blood
Welch JS, Petti AA, Miller CA, et al. (2016) TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes. The New England Journal of Medicine. 375: 2023-2036
Griffith M, Griffith OL, Krysiak K, et al. (2016) Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B lymphoblastic leukemia. Experimental Hematology
Cole CB, Verdoni AM, Ketkar S, et al. (2016) PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia. The Journal of Clinical Investigation. 126: 85-98
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