Grazia Isaya

Affiliations: 
Biochemistry and Molecular Biology College of Medicine - Mayo Clinic 
Area:
Biochemistry, Molecular Biology, Genetics
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"Grazia Isaya"
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Publications

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Ahlgren EC, Fekry M, Wiemann M, et al. (2017) Iron-induced oligomerization of human FXN81-210 and bacterial CyaY frataxin and the effect of iron chelators. Plos One. 12: e0188937
Fekry M, Alshokry W, Grela P, et al. (2017) SAXS and stability studies of iron-induced oligomers of bacterial frataxin CyaY. Plos One. 12: e0184961
Gakh O, Ranatunga W, Galeano BK, et al. (2017) Defining the Architecture of the Core Machinery for the Assembly of Fe-S Clusters in Human Mitochondria. Methods in Enzymology. 595: 107-160
Galeano BK, Ranatunga W, Gakh O, et al. (2017) Zinc and the iron donor frataxin regulate oligomerization of the scaffold protein to form new Fe-S cluster assembly centers. Metallomics : Integrated Biometal Science
Gakh O, Ranatunga W, Smith DY, et al. (2016) Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery. The Journal of Biological Chemistry
Soderberg CG, Gillam ME, Ahlgren EC, et al. (2016) The Structure of the Complex Between Yeast Frataxin and Ferrochelatase: Characterization and pre-Steady State Reaction of Ferrous Iron Delivery and Heme Synthesis. The Journal of Biological Chemistry
Ranatunga W, Gakh O, Galeano BK, et al. (2016) Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: The Sub-Complex Formed by the Iron Donor, Yfh1, and the Scaffold, Isu1. The Journal of Biological Chemistry
Yoon G, Delague V, Mégarbané A, et al. (2015) Reply: Autosomal recessive cerebellar ataxia caused by a homozygous mutation in PMPCA. Brain : a Journal of Neurology
Jobling RK, Assoum M, Gakh O, et al. (2015) PMPCA mutations cause abnormal mitochondrial protein processing in patients with non-progressive cerebellar ataxia. Brain : a Journal of Neurology. 138: 1505-17
Isaya G. (2014) Mitochondrial iron-sulfur cluster dysfunction in neurodegenerative disease. Frontiers in Pharmacology. 5: 29
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